What Is
Infertility
About 14% of couples who seek to
have a baby will experience infertility. Some authorities recommend that
if a couple fails to conceive after a year during which sex has been
frequent, then they should consult a fertility expert. Women who are over
30, however, may want to begin exploring their options if they don't
become pregnant within six months.
About 50% of couples who
get expert help for their infertility can achieve pregnancy within two
years with appropriate treatment of the woman, the man, or both. Males and
females each account for 40% of infertility; in the remaining 20%, either
both partners are responsible or the cause is unclear.
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What Are Some Causes Of
Infertility
Causes of
infertility include a wide range of physical, as well as emotional
factors. Approximately 30 to 40% of all infertility is due to a
"male" factor (such as retrograde ejaculation, impotence,
hormone deficiency, environmental pollutants, scarring from
sexually-transmitted disease, or decreased sperm count due to heavy
marijuana use or prescription drugs such as cimetidine, spironolactone,
and nitrofurantoin).
A "female" factor (for example, scarring from
sexually-transmitted disease, ovulation dysfunction, poor nutrition,
hormone imbalance, cysts, or cancer of the ovarians or uterus, pelvic
infection or tumor, or transport system abnormality from the cervix
through the Fallopian tubes) is responsible for 40 to 50% of infertility
in couples. The remaining 10 to 30% may be caused by contributing factors
by both partners, or no cause can be adequately identified.
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What Factors May Increase
Ones Risk Of Infertility
It is estimated that 10 to 20% of
couples will be unable to conceive after one year of attempting to become
pregnant. It is important that pregnancy be attempted for an extended
period (at least one year); the chances for pregnancy occurring in young
healthy couples, having intercourse regularly, is only 25 to 30% per
month.
Increased risk for infertility is associated with:
- having multiple sexual partners
(therefore increasing the risk for STDs)
- having a sexually-transmitted disease
- having a past history of PID (pelvic
inflammatory disease) (after single episode 23% of women become
infertile)
- age - A woman's age, or more accurately,
the age of her eggs, plays a major role in fertility. At age 25, the
chance of getting pregnant within the first six months of trying is
75%; at age 40, it is only 22%. This decrease in fertility appears to
be due to a higher rate of chromosomal damage that occurs in the eggs
as time goes by.
- weight - Although most of a woman's
estrogen is manufactured in her ovaries, 30% is produced in fat cells.
Because a normal hormonal balance is essential for the process of
conception, it is not surprising that extreme weight levels, either
high or low, can contribute to infertility.
- having mumps orchitis (men)
- having a past medical history inclusive
of DES exposure (men or women)
- having eating disorders (women)
- having anovulatory (with out mensus)
menstrual cycles (Marathon runners, dancers, and others who exercise
very intensely may find that their menstrual cycle is abnormal and
fertility is impaired).
- having a chronic disease (such as
diabetes)
- depression - depression is very common
in women who are trying to become pregnant. In fact, depression may
have a direct effect on hormones that regulate reproduction.
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How Do I Find The Right
Doctor
Believe it or not, there is a
difference between an obstetrician/gynecologist and an infertility
specialist. An ob/gyn is a medical doctor who incorporates infertility as
just one minor area of his/her general practice. There are many ob/gyns
that claim to be specialists in infertility, this is misleading due to the
fact that only about 500 out of 28,000 ob/gyn practitioners are board
certified specialists in infertility, also known as reproductive
endocrinologists. While all of these physicians are gynecologists,
reproductive endocrinologists practices are set up solely to assist in
reproduction. Because of this, they have specialized ultrasound equipment,
expanded office hours for cycling patients and the necessary surgical and
laboratory facilities to accommodate their infertile patients daily
needs.
The five most important questions to ask
your doctor before entering into treatment are:
- What is your background and training?
- How many of these procedures do you
perform annually?
- What is your pregnancy rate per
procedure?
- What is you "baby rate" per
procedure?
- Who does more of these procedures
annually than you do, and how do their success rates compare to yours?
This is a lie detector test which can be checked against calling
your local Resolve chapter and you can requesting current data on
physicians in your community who perform various procedures that are
of interest to you.
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Tests Before Treatment (The
Basic Workup)
It is always hard to wait for
something you want right now, but tests are an intricate part of the
treatment program of infertility. Your physician will be performing a
series of tests in hopes of closing in on your possible problem areas and
determining the exact cause of your infertility. With out tests, treatment
can not follow.
1. Medical History and
Physical Examination
The first step in
any infertility work up is a complete medical history and physical
examination. Sexual technique and timing, menstrual history, family
history of infertility, lifestyle issues, such as drug, alcohol, and
caffeine consumption, and a profile of the patient's general medical and
emotional health can help the physician decide on appropriate tests. The
male partner should also be given a physical examination.
2. Laboratory Tests
Blood and urine
tests are taken to evaluate hormone levels. Urine tests can measure
preovulatory LH surges. To rule out luteal phase defect, the physician may
take tissue samples of the uterus one or two days before a period to
determine if the corpus luteum is adequately producing progesterone. If a
woman is having abnormal or irregular menstruation, measurements of FSH
and LH levels are taken to detect premature menopause (high FSH and LH) or
polycystic ovary syndrome (high LH and low FSH). Blood tests for prolactin
levels and thyroid function are also measured. Cervical mucus is examined
after intercourse at mid-cycle (when ovulation should occur) to determine
whether it has the right qualities to promote sperm passage and to see if
the sperm are viable and motile. This so-called postcoital test has been
in use since 1866. Some experts now believe, however, that abnormal
postcoital test results have no effect on pregnancy rates and that they
lead to unnecessary fertility procedures. Tissue samples taken from the
cervix may be cultured to rule out infection. Tests for hypothyroidism and
diabetes should be considered in women with recent ovarian failure that is
not caused by genetic abnormalities. Tests will also be performed on the
male partner to determine sperm count and viability.
3. Testing for Fallopian
Tube and Uterine Abnormalities
Laparoscopy
http://infertility.about.com/health.infertility/gi/dynamic/offsite.htm/site=http://www.obgyn.net/ENGLISH/PUBS/FEATURES/lap.htm
Hysterosalpingography
http://infertility.about.com/health/infertility/gi/dynamic/offsite.htm?site=http://www.advancedfertility.com/hsg.html
Ultrasound
Ultrasound is a noninvasive method
for evaluating the uterus and ovaries by using sound waves rather than
x-rays. Ultrasound carries little risk or discomfort while producing clear
images that enable the physician to count any mature follicles present and
examine the endometrium. Fibroid tumors and ovarian cysts can be diagnosed
as well.
Other tests may include the following:
- Semen analysis to evaluate ejaculate;
collected after 2 to 3 days of complete abstinence to determine volume
and viscosity of semen and sperm count, motility, swimming speed, and
shape.
- Chromosomal Testing - Tests that analyze
sex chromosomes may help predict which couples are more apt to fail or
succeed using assisted reproductive technologies. One, called
fluorescent in situ hybridization, detects sperm abnormalities. Others
look at the chromosomes of both the man and woman to detect abnormal
patterns.
- Measuring basal body temperature--taking
the woman's temperature each morning before arising in an effort to
note the 0.4 to 1.0 degree Fahrenheit temperature increase associated
with presumptive ovulation.
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Treatment
Treatment depends on the cause of
infertility for any given couple. It may range from simple education and
counseling, to the use of medications that treat infections or promote
ovulation, to highly sophisticated medical procedures such as in-vitro
fertilization.
For more in-depth information use this link: http://health.excite.com/content/dmk/dmk_article_3961653
Artificial
Insemination
Artificial insemination (AI) is a
procedure that places the sperm inside the woman's vagina, uterus, or
cervix. There are several variations: intracervical insemination places
sperm in the cervix (used for cervical mucus problems or vaginal
abnormalities); intrauterine insemination (IUI) and intratubal
insemination place the sperm higher up and are effective for more severe
problems.
http://infertility.about.com/health/infertility/msubdonor.htm?rnk=r&terms=artificial+insemination
Assisted Reproductive
Technologies:
Assisted reproductive technologies
(ART) are procedures that retrieve eggs from the ovary and reimplant them.
The most common one is in vitro fertilization (IVF). More recent ART
procedures include gamete intrafallopian transfer (GIFT), zygote
intrafallopian transfer (ZIFT), and intracytoplasmic sperm injection (ICSI).
Assisted Reproductive
Technologies: Specific Procedures
In Vitro Fertilization (IVF)
Gamete/Zygote Intrafallopian Transfer
(GIFT)
IntraCytoplasmic Sperm Injection (ICSI)
Use this links for in-depth information on
ART:
http://www.fertilityinstitute.com/advanced.html
http://infertility.miningco.com/health/infertility/library/weekly/aa042900a.htm
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Expectations
And Complications
A probable cause can be determined
for about 85 to 90% of infertile couples. Appropriate therapy (not
including advanced techniques such as in-vitro fertilization) allows
pregnancy to occur in 50 to 60% of previously infertile couples. Without
any treatment intervention 15 to 20% of couples previously diagnosed as
infertile will eventually become pregnant.
Planning for Treatment
Outcomes
There often is no way to predict
which couples will eventually conceive; some with multiple problems will
overcome great odds, while seemingly fertile couples fail to conceive.
Many of the new treatments are remarkable, but a live birth is never
guaranteed. The emotional stress of failure can be devastating even on the
most loving and affectionate relationships. Even in the absence of
failure, the road to pregnancy can be very difficult. Couples must be
prepared to make many sacrifices, both financial and emotional, before
undergoing this process. A successful pregnancy often depends on repeated
attempts. Some couples become addicted to treatment, and continue with
fertility procedures until they are emotionally and financially drained.
Partners should decide in advance how many and what kind of procedures
they believe will be financially and emotionally acceptable and attempt to
determine a final limit. They should also explore in advance alternatives
such as adoption, childlessness, and donor sperm. Determining all options
as early as possible in the process can reduce anxiety during treatments
and feelings of hopelessness if they don't work out.
Complications
Although infertility itself does
not cause physical illness, the psychological impact of infertility upon
individuals or couples affected by it may be severe. Marital problems,
including divorce, as well as individual depression and anxiety are
commonly encountered.
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